The Annenberg Center for Health Sciences was founded to resolve issues vital to health and science, provide continuing professional education, and promote public wellness.

In 1979, Ambassador and Mrs. Walter H. Annenberg donated $4 million for health sciences, and construction began on the Annenberg Center for Health Sciences in 1980. The Annenberg Center hosted its first medical conferences in 1982. The Honorable Walter H. Annenberg's vision was to establish "an unmatched facility where leaders in education, medicine, government, and industry will gather to contemplate issues of the next century."

The Annenberg Center plays many roles today. It hosts national and international conferences exploring contemporary health care issues, and is a leader in continuing education for local, national, and international audiences.

The Annenberg Center is a public benefit 501(c) (3) corporation.